Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177577 | 0.86 | GPBAR1 (0.36) | — | |
| SCHEMBL20177855 | 0.84 | — | — | |
| SCHEMBL20177504 | 0.83 | KDM1A (0.32) | KDM1AKDM1B | |
| SCHEMBL20177592 | 0.80 | ESRRG (0.34) | — | |
| SCHEMBL20177736 | 0.80 | KDM1A (0.34) | KDM1AKDM1B | |
| SCHEMBL20177686 | 0.77 | — | — | |
| SCHEMBL19559541 | 0.75 | FPR2 (0.34) | MAP2K1 | |
| SCHEMBL20177903 | 0.75 | — | — | |
| SCHEMBL16785344 | 0.73 | FPR1 (0.35) | — | |
| SCHEMBL18117741 | 0.73 | FPR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |