Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177902 | 0.84 | GRM4 (0.39) | PDE4APDE4BPDE4CPDE4DGRM5 | |
| SCHEMBL20177560 | 0.83 | ALDH1A1 (0.43) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL26456470 | 0.80 | GRM5 (0.38) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL26731428 | 0.79 | MAPT (0.38) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL26727727 | 0.78 | GPR6 (0.36) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL26456544 | 0.78 | POLB (0.39) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL26729331 | 0.78 | GRM5 (0.37) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL26724436 | 0.78 | FPR1 (0.37) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL26455811 | 0.78 | POLB (0.39) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL26723799 | 0.78 | MAPT (0.43) | PDE4APDE4BPDE4CPDE4DTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |