Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177834 | 0.84 | PDE4A (0.44) | GRM4GRM5PDE4APDE4BPDE4C | |
| SCHEMBL20177851 | 0.79 | BRD4 (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20177560 | 0.68 | ALDH1A1 (0.43) | GRM5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20177564 | 0.61 | KDM1A (0.32) | — | |
| SCHEMBL20177500 | 0.61 | DPP4 (0.43) | — | |
| SCHEMBL17514687 | 0.61 | KDM1A (0.35) | KMT2A | |
| SCHEMBL20177653 | 0.61 | GSK3B (0.48) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL18640812 | 0.60 | BPTF (0.44) | GRM5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20177816 | 0.59 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL20177572 | 0.59 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |