SCHEMBL20177936

SCHEMBL20177936

N[C@@H]1c2nncn2C[C@H]1c1c(F)cc(Br)cc1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.32
KDM1B Q8NB78 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20177625 0.83 AADAT (0.33) KDM1A
SCHEMBL20177716 0.78 KDM1A (0.34) KDM1AKDM1B
SCHEMBL20177859 0.69 ADRA1A (0.31)
SCHEMBL20177640 0.68 DPP4 (0.38) KDM1A
SCHEMBL20177616 0.64 FPR2 (0.42) KDM1AKDM1B
SCHEMBL20177760 0.64 ADRA1A (0.31)
SCHEMBL18264318 0.59 FPR2 (0.34) KDM1A
SCHEMBL17514687 0.56 KDM1A (0.35) KDM1AKDM1B
SCHEMBL31137370 0.56 KDM1A (0.34) KDM1AKDM1B
SCHEMBL29013524 0.55 KDM1A (0.34) KDM1AKDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018092916-A1 NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE 宇部興産株式会社 2018-05-24 WO disclosed