Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174383 | 0.84 | ALDH1A1 (0.41) | RAB9ASMN1; SMN2NPC1TP53TSHR | |
| SCHEMBL20174394 | 0.81 | KDM4E (0.41) | RAB9ASMN1; SMN2GRM5NPC1TP53 | |
| SCHEMBL20174711 | 0.78 | SMN1; SMN2 (0.40) | RAB9ASMN1; SMN2GRM5NPC1TP53 | |
| SCHEMBL20174414 | 0.77 | ALDH1A1 (0.38) | RAB9ASMN1; SMN2NPC1TP53TSHR | |
| SCHEMBL20174399 | 0.76 | KDM4E (0.38) | RAB9ASMN1; SMN2GRM5NPC1TP53 | |
| SCHEMBL20174395 | 0.76 | PLA2G2A (0.33) | SMN1; SMN2TP53TSHRKDM4EALDH1A1 | |
| SCHEMBL20179304 | 0.75 | RAB9A (0.33) | RAB9ASMN1; SMN2GRM5NPC1TP53 | |
| SCHEMBL20174320 | 0.73 | MAPT (0.33) | SMN1; SMN2TP53TSHRPDK2KDM4E | |
| SCHEMBL18732054 | 0.72 | ALDH1A1 (0.39) | RAB9ASMN1; SMN2NPC1TP53TSHR | |
| SCHEMBL22326572 | 0.72 | PDK2 (0.30) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | RAB9A 2250/4885SMN1; SMN2 3407/4885GRM5 2692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.