Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 11/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17010264 | 0.81 | XDH (0.55) | XDHSLC22A12MEN1KMT2AALDH1A1 | |
| SCHEMBL20179443 | 0.74 | XDH (0.48) | XDHSLC22A12MEN1KMT2AALDH1A1 | |
| SCHEMBL22381442 | 0.72 | XDH (0.44) | XDHSLC22A12MEN1KMT2AALDH1A1 | |
| SCHEMBL20179445 | 0.71 | XDH (0.42) | XDHSLC22A12MEN1KMT2AALDH1A1 | |
| SCHEMBL17010238 | 0.66 | XDH (0.44) | XDHSLC22A12MEN1KMT2AALDH1A1 | |
| SCHEMBL27741350 | 0.65 | KMT2A (0.47) | SLC22A12MEN1KMT2AMAPTTDP1 | |
| SCHEMBL20179455 | 0.62 | XDH (0.60) | XDHSLC22A12MEN1KMT2AALDH1A1 | |
| SCHEMBL20179671 | 0.62 | XDH (0.31) | XDH | |
| SCHEMBL20997681 | 0.61 | MASP2 (0.39) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL20997879 | 0.61 | CES2 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018005192-A9 | COMPOUNDS AND THEIR USE FOR REDUCING URIC ACID LEVELS | ACQUIST LLC (US) | 2018-05-24 | — | — | WO | disclosed |