Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179443 | 0.75 | XDH (0.48) | XDHKMT2AMEN1ALDH1A1SLC22A12 | |
| SCHEMBL20179663 | 0.71 | XDH (0.42) | XDHKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL20179665 | 0.64 | XDH (0.34) | XDHGAAPOLBMAPTTDP1 | |
| SCHEMBL20179671 | 0.59 | XDH (0.31) | XDH | |
| SCHEMBL20997681 | 0.58 | MASP2 (0.39) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL20997690 | 0.57 | LMNA (0.52) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL20998018 | 0.57 | OGG1 (0.52) | ALDH1A1GAAPOLBMAPTRAB9A | |
| SCHEMBL20997849 | 0.57 | MAOA (0.42) | KMT2AMEN1RAB9A | |
| SCHEMBL20997871 | 0.57 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL20179476 | 0.57 | XDH (0.75) | XDHKMT2AMEN1ALDH1A1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018005192-A9 | COMPOUNDS AND THEIR USE FOR REDUCING URIC ACID LEVELS | ACQUIST LLC (US) | 2018-05-24 | — | — | WO | disclosed |