Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015741 | 0.83 | L3MBTL1 (0.44) | L3MBTL1CCR1CCR8KDM4ELMNA | |
| SCHEMBL2015203 | 0.82 | CDK1 (0.46) | L3MBTL1CCR1CCR8KDM4ELMNA | |
| SCHEMBL2015005 | 0.80 | PIK3CD (0.44) | L3MBTL1CCR1CCR8KDM4ELMNA | |
| SCHEMBL2014257 | 0.78 | KDM4E (0.42) | L3MBTL1CCR1CCR8KDM4ELMNA | |
| SCHEMBL2014459 | 0.76 | CDK1 (0.62) | L3MBTL1KDM4ELMNATDP1HTT | |
| SCHEMBL2017970 | 0.75 | KDM4E (0.44) | L3MBTL1CCR1CCR8KDM4ELMNA | |
| SCHEMBL1811084 | 0.72 | HIF1A (0.49) | L3MBTL1CCR1CCR8KDM4ELMNA | |
| SCHEMBL2015201 | 0.72 | L3MBTL1 (0.46) | L3MBTL1CCR1CCR8KDM4ELMNA | |
| SCHEMBL2015740 | 0.72 | L3MBTL1 (0.43) | L3MBTL1CCR1CCR8KDM4ELMNA | |
| SCHEMBL3904765 | 0.71 | DPP4 (0.42) | KDM4ELMNATDP1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |