Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.30 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22166905 | 0.85 | IL1B (0.30) | — | |
| SCHEMBL21191242 | 0.82 | ITGB3 (0.30) | ITGB3ITGA2B | |
| SCHEMBL17933273 | 0.77 | UGT2B7 (0.31) | — | |
| SCHEMBL26999943 | 0.77 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL13929717 | 0.73 | CHRNB2 (0.52) | CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL20179889 | 0.73 | PTGIR (0.32) | PTGIRPTGDRCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL17933276 | 0.72 | APLNR (0.32) | — | |
| SCHEMBL13695531 | 0.72 | CHRNB2 (0.48) | CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL21191219 | 0.71 | — | — | |
| SCHEMBL26211844 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018090862-A1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-05-24 | — | — | WO | disclosed |