SCHEMBL20179914

SCHEMBL20179914

CC(C)(C)C(=O)Oc1ccc2c(c1F)OCCC=C2OS(=O)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20179915 0.90 ELANE (0.32) ELANE
SCHEMBL20179674 0.89 ELANE (0.31) ELANE
SCHEMBL20165285 0.82 ELANE (0.32) ELANE
SCHEMBL23335926 0.80 ELANE (0.32) ELANE
SCHEMBL20179806 0.78 ELANE (0.38) ELANE
SCHEMBL20179679 0.78 LMNA (0.33) ELANE
SCHEMBL20179916 0.77
SCHEMBL20165058 0.71 ELANE (0.32) ELANE
SCHEMBL29756833 0.71 ELANE (0.32) ELANE
SCHEMBL20165284 0.71 LTB4R (0.35) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018091153-A1 NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF SANOFI (FR) 2018-05-24 WO disclosed