⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179679 | 0.89 | LMNA (0.33) | — | |
| SCHEMBL20165329 | 0.82 | — | — | |
| SCHEMBL20179806 | 0.82 | ELANE (0.38) | — | |
| SCHEMBL20179674 | 0.80 | ELANE (0.31) | — | |
| SCHEMBL20179914 | 0.77 | ELANE (0.32) | — | |
| SCHEMBL20179915 | 0.77 | ELANE (0.32) | — | |
| SCHEMBL20179641 | 0.71 | ELANE (0.39) | — | |
| SCHEMBL20165091 | 0.71 | PKM (0.31) | — | |
| SCHEMBL20165387 | 0.71 | LMNA (0.33) | — | |
| SCHEMBL20165857 | 0.71 | ELANE (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |