Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179916 | 0.89 | — | — | |
| SCHEMBL20179806 | 0.82 | ELANE (0.38) | MAPTELANE | |
| SCHEMBL20165387 | 0.82 | LMNA (0.33) | LMNAMAPTNPSR1ELANE | |
| SCHEMBL20179915 | 0.80 | ELANE (0.32) | ELANE | |
| SCHEMBL20179914 | 0.78 | ELANE (0.32) | ELANE | |
| SCHEMBL20179674 | 0.77 | ELANE (0.31) | ELANE | |
| SCHEMBL20179641 | 0.72 | ELANE (0.39) | MAPTELANE | |
| SCHEMBL20165091 | 0.71 | PKM (0.31) | ELANE | |
| SCHEMBL20165329 | 0.71 | — | — | |
| SCHEMBL23335926 | 0.70 | ELANE (0.32) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |