SCHEMBL20179935

SCHEMBL20179935

c1ccc([Si](c2ccccc2)(c2cccc(-c3cccc4c3sc3ccccc34)c2)c2cccc(-c3ccc(-c4ccc5c(c4)sc4c([Si](c6ccccc6)(c6ccccc6)c6cccc7c6sc6ccccc67)cccc45)c4c3sc3ccccc34)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.45
PRKDC P78527 1/20 0.36
LIMK1 P53667 4/20 0.33
PARP14 Q460N5 1/20 0.31
TNKS O95271 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
F9 P00740 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24187077 0.90 ALOX5 (0.45) ALOX5PRKDCLIMK1PARP14TNKS
SCHEMBL18410796 0.90 ALOX5 (0.46) ALOX5PRKDCLIMK1PARP14TNKS
SCHEMBL21264463 0.89 ALOX5 (0.46) ALOX5PRKDCLIMK1PARP14TNKS
SCHEMBL23176627 0.88 ALOX5 (0.46) ALOX5PRKDCLIMK1PARP14TNKS
SCHEMBL18541210 0.86 ALOX5 (0.49) ALOX5PRKDCLIMK1PARP14TNKS
SCHEMBL17754640 0.86 ALOX5 (0.51) ALOX5PRKDCLIMK1PARP14TNKS
SCHEMBL17754651 0.86 ALOX5 (0.50) ALOX5PRKDCLIMK1PARP14TNKS
SCHEMBL17754642 0.85 ALOX5 (0.51) ALOX5PRKDCLIMK1PARP14TNKS
SCHEMBL126275 0.83 ALOX5 (0.57) ALOX5PRKDCLIMK1PARP14TNKS
SCHEMBL29306737 0.83 ALOX5 (0.57) ALOX5PRKDCLIMK1PARP14TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11325932-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-05-10 US disclosed
US-20200283462-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION, 2020-09-10 US disclosed
US-20180145268-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200283462-A1 Organic Electroluminescent Materials and Devices L1CAM, KCNN4, ITGB4 ALOX5 1418/4885PRKDC 4034/4885LIMK1 776/4885
US-11325932-B2 Organic electroluminescent materials and devices L1CAM, RTN4, KCNN4 ALOX5 1227/4885PRKDC 3516/4885LIMK1 1368/4885
US-20180145268-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, SOAT2 ALOX5 812/4885PRKDC 4258/4885LIMK1 1400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.