SCHEMBL20180147

SCHEMBL20180147

COc1c(C(C)(C)C)cc2c(c1-c1cc(C)cc(C)c1)CC(C)C2=O

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 13/20 0.42
PTGS2 P35354 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CNR2 P34972 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22863196 1.00 ACHE (0.42) ACHEPTGS2ALDH1A1TSHRTDP1
SCHEMBL20165703 1.00 ACHE (0.42) ACHEPTGS2ALDH1A1TSHRTDP1
SCHEMBL27433076 0.91 ACHE (0.45) ACHEPTGS2ALDH1A1TSHRTDP1
SCHEMBL14645803 0.88 ACHE (0.42) ACHEPTGS2
SCHEMBL14645764 0.85 ACHE (0.45) ACHE
SCHEMBL27432437 0.85 ACHE (0.42) ACHEPTGS2ALDH1A1TSHRTDP1
SCHEMBL31342804 0.85
SCHEMBL20165758 0.85 ACHE (0.40) ACHEPTGS2
SCHEMBL31355494 0.85 CNR2 (0.33) CNR2
SCHEMBL21451184 0.85 CNR2 (0.33) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682201-A1 BETA-NUCLEATED MULTIMODAL COPOLYMERS Borealis GmbH (AT) 2026-01-21 EP disclosed
WO-2025051400-A1 METHODS OF PRODUCING METALLOCENE CATALYST COMPONENTS BOREALIS AG (AT) 2025-03-13 WO disclosed
EP-3820939-B1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH IMPROVED BALANCE OF PROPERTIES BOREALIS AG (AT) 2024-06-05 EP disclosed
US-11952481-B2 Heterophasic polypropylene composition with high flexibility and softness BOREALIS AG (AT) 2024-04-09 US disclosed
CN-111527140-B Heterophasic polypropylene composition with high flexibility and high softness 北欧化工公司 2023-11-17 CN disclosed
US-11807655-B2 Catalysts BOREALIS AG (AT) 2023-11-07 US disclosed
US-11807655-B2 Catalysts BOREALIS AG (AT) 2023-11-07 US disclosed
US-11807655-B2 Catalysts BOREALIS AG (AT) 2023-11-07 US disclosed
CN-113474406-B Nucleated propylene polymer compositions with high toughness 博里利斯股份公司 2023-09-15 CN disclosed
US-11702487-B2 Process for preparing propylene polymers BOREALIS AG (AT) 2023-07-18 US disclosed
WO-2019179959-A1 CATALYSTS FOR OLEFIN POLYMERIZATION BOREALIS AG (AT) 2019-09-26 WO disclosed
WO-2019141546-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH HIGH FLEXIBILITY AND SOFTNESS BOREALIS AG (AT) 2019-07-25 WO disclosed
WO-2019052820-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2019-03-21 WO disclosed
WO-2019052820-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2019-03-21 WO disclosed
EP-3456776-A1 POLYPROPYLENE COMPOSITION Borealis AG (AT) 2019-03-20 EP disclosed
EP-3456776-A1 POLYPROPYLENE COMPOSITION Borealis AG (AT) 2019-03-20 EP disclosed
WO-2019007655-A1 PROCESS FOR PREPARING HETEROPHASIC PROPYLENE COPOLYMERS BOREALIS AG (AT) 2019-01-10 WO disclosed
WO-2019007655-A1 PROCESS FOR PREPARING HETEROPHASIC PROPYLENE COPOLYMERS BOREALIS AG (AT) 2019-01-10 WO disclosed
WO-2018122134-A1 CATALYSTS BOREALIS AG (AT) 2018-07-05 WO disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807655-B2 Catalysts SOD1, MT-CO2, MT-CO1 ACHE 3437/4885PTGS2 2491/4885ALDH1A1 1567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.