SCHEMBL20180263

SCHEMBL20180263

CC1(C)OB(c2cccc(Nc3ccccc3C(=N)c3ccccc3)c2)OC1(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.39
SIRT2 Q8IXJ6 6/20 0.39
LPL P06858 2/20 0.37
LIPG Q9Y5X9 2/20 0.37
SIRT1 Q96EB6 3/20 0.36
P4HB P07237 1/20 0.36
AKR1C3 P42330 4/20 0.36
AKR1C2 P52895 4/20 0.36
TAS2R14 Q9NYV8 2/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
AKR1C4 P17516 2/20 0.34
AKR1C1 Q04828 2/20 0.34
AKR1B10 O60218 1/20 0.34
AKR1B1 P15121 1/20 0.34
PDGFRB P09619 1/20 0.34
KDR P35968 1/20 0.34
CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20615277 0.93 MAPT (0.37) EGFRSIRT2LPLLIPGSIRT1
SCHEMBL20180122 0.91 EGFR (0.39) EGFRSIRT2LPLLIPGSIRT1
SCHEMBL20180255 0.88 LIPG (0.44) EGFRSIRT2LPLLIPGSIRT1
SCHEMBL20180251 0.84 LIPG (0.42) EGFRSIRT2LPLLIPGSIRT1
SCHEMBL20615296 0.84 EGFR (0.35) EGFRSIRT2LPLLIPGP4HB
SCHEMBL20180141 0.81 LPL (0.37) EGFRLPLLIPGP4HBAKR1C3
SCHEMBL20615350 0.81 LIPG (0.44) EGFRSIRT2LPLLIPGSIRT1
SCHEMBL3758531 0.78 LIPG (0.50) EGFRLPLLIPGP4HBPTGS1
SCHEMBL25491284 0.77 EGFR (0.42) EGFRLPLLIPGP4HBMAPT
SCHEMBL20180180 0.76 EGFR (0.41) EGFRLPLLIPGMAPTPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018093107-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2018-05-24 WO disclosed