SCHEMBL3758531

SCHEMBL3758531

CC1(C)OB(c2cccc(Nc3ccccc3)c2)OC1(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 7/20 0.50
LPL P06858 6/20 0.50
ALDH1A1 P00352 3/20 0.48
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 2/20 0.48
AR P10275 1/20 0.48
EGFR P00533 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42
HSD17B10 Q99714 3/20 0.40
PDGFRB P09619 1/20 0.40
KDR P35968 1/20 0.40
CA1 P00915 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28385379 0.88 LIPG (0.51) LIPGLPLALDH1A1MEN1MAPT
SCHEMBL25237681 0.88 EGFR (0.51) LIPGLPLALDH1A1MEN1MAPT
SCHEMBL14128820 0.86 AKR1C3 (0.43) LIPGLPLALDH1A1MEN1MAPT
SCHEMBL1129188 0.84 LPL (0.65) LIPGLPLALDH1A1MEN1MAPT
SCHEMBL25491284 0.83 EGFR (0.42) LIPGLPLMEN1MAPTKMT2A
SCHEMBL12314741 0.83 CA1 (0.51) LIPGLPLALDH1A1EGFRTDP1
SCHEMBL12314376 0.83 POLB (0.53) ALDH1A1MEN1MAPTKMT2AEGFR
SCHEMBL29611597 0.83 LIPG (0.49) LIPGLPLEGFRTSHRPDGFRB
SCHEMBL150942 0.83 LIPG (0.49) LIPGLPLEGFRTSHRPDGFRB
SCHEMBL20180180 0.82 EGFR (0.41) LIPGLPLALDH1A1MAPTEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111732611-B Novel tetradentate platinum complexes 通用显示公司 2022-08-23 CN disclosed
WO-2022035097-A1 ORGANIC LIGHT-EMITTING DEVICE AND COMPOSITION FOR FORMING ORGANIC MATERIAL LAYER 엘티소재주식회사 2022-02-17 WO disclosed
US-10991890-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same DUK SAN NEOLUX CO., LTD. (KR) 2021-04-27 US disclosed
CN-111732611-A Novel tetradentate platinum complexes 通用显示公司 2020-10-02 CN disclosed
CN-106749425-B Novel tetradentate platinum complexes 通用显示公司 2020-07-14 CN disclosed
US-10381580-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
US-10381580-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
US-20180151816-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-31 US disclosed
US-20180151816-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-31 US disclosed
US-20180151816-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-31 US disclosed
US-8871361-B2 Tetradentate platinum complexes UNIVERSAL DISPLAY CORPORATION (US) 2014-10-28 US disclosed
US-8530480-B2 Substituted pyrimidinyl-amines as protein kinase inhibitors THE SCRIPPS RESEARCH INSTITUTE (US) 2013-09-10 US disclosed
US-20130231336-A1 SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS THE SCRIPPS RESEARCH INSTITUTE (US) 2013-09-05 US disclosed
US-20120223634-A1 NOVEL TETRADENTATE PLATINUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2012-09-06 US disclosed
US-20120223634-A1 NOVEL TETRADENTATE PLATINUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2012-09-06 US disclosed
US-20120223634-A1 NOVEL TETRADENTATE PLATINUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2012-09-06 US disclosed
WO-2012116231-A2 NOVEL TETRADENTATE PLATINUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2012-08-30 WO disclosed
US-20100298312-A1 SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS THE SCRIPPS RESEARCH INSTITUTE (US) 2010-11-25 US disclosed
EP-2200436-A1 SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS The Scripps Research Institute (US) 2010-06-30 EP disclosed
WO-2009032861-A1 SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS THE SCRIPPS RESEARCH INSTITUTE (US) 2009-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10991890-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same NOTUM, OR10J3, PER2 LIPG 2148/4885LPL 1751/4885ALDH1A1 210/4885
US-10381580-B2 Organic electroluminescent materials and devices TEC, EML4, TPR LIPG 4398/4885LPL 4102/4885ALDH1A1 2604/4885
US-20130231336-A1 SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS MAP3K20, MAP3K5, MAP3K7 LIPG 4205/4885LPL 4544/4885ALDH1A1 4097/4885
US-20180151816-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TEC, EML4, TPR LIPG 4398/4885LPL 4102/4885ALDH1A1 2604/4885
US-20100298312-A1 SUBSTITUTED PYRIMIDINYL-AMINES AS PROTEIN KINASE INHIBITORS MAP3K20, MAP3K5, MAP3K7 LIPG 4205/4885LPL 4544/4885ALDH1A1 4097/4885
US-20120223634-A1 NOVEL TETRADENTATE PLATINUM COMPLEXES PDCD1LG2, TEC, TPR LIPG 4596/4885LPL 4301/4885ALDH1A1 3589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.