SCHEMBL20180489

SCHEMBL20180489

Cc1cc(C)[n+](C)c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 11/20 0.48
HTT P42858 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MAPT P10636 2/20 0.40
CYP1A2 P05177 4/20 0.39
CYP2A6 P11509 1/20 0.39
KDM4E B2RXH2 2/20 0.37
PRKCA P17252 2/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
GMNN O75496 1/20 0.36
ALDH1A1 P00352 1/20 0.36
F2 P00734 1/20 0.36
LMNA P02545 1/20 0.36
ESR1 P03372 1/20 0.36
TP53 P04637 1/20 0.36
PGR P06401 1/20 0.36
POLB P06746 1/20 0.36
CHRM2 P08172 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11075861 0.81 ACHE (0.39) ACHEHTTSMN1; SMN2MAPTKDM4E
SCHEMBL7256323 0.79 ACHE (0.45) ACHEHTTSMN1; SMN2MAPTCYP1A2
SCHEMBL337016 0.79 PRKCA (0.57) ACHEHTTSMN1; SMN2MAPTCYP1A2
SCHEMBL14982714 0.79 ACHE (0.45) ACHEHTTSMN1; SMN2MAPTCYP1A2
Iodide SCHEMBL336306 0.78 PRKCA (0.58) ACHEHTTSMN1; SMN2MAPTCYP1A2
Iodide SCHEMBL29918121 0.78 PRKCA (0.58) ACHEHTTSMN1; SMN2MAPTCYP1A2
Iodide SCHEMBL10549487 0.78 ACHE (0.44) ACHEHTTSMN1; SMN2MAPTCYP1A2
SCHEMBL3391710 0.77 MAPT (0.59) ACHEHTTSMN1; SMN2MAPTCYP1A2
SCHEMBL18535214 0.77 MAPT (0.39) ACHEHTTSMN1; SMN2MAPTCYP1A2
SCHEMBL8019789 0.76 ACHE (0.42) ACHESMN1; SMN2MAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024013006-A1 CROSSLINKABLE FLUOROPOLYMER COMPOSITIONS FOR SEALING FUEL CELLS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2024-01-18 WO disclosed
EP-3941974-B1 FLUOROELASTOMER COMPOSITION SOLVAY SPECIALTY POLYMERS IT (IT) 2023-11-08 EP disclosed
US-20220135774-A1 FLUOROELASTOMER COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2022-05-05 US disclosed
US-11059922-B2 Method for cross-linking polymers SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2021-07-13 US disclosed
US-10766989-B2 Fluoroelastomer composition SOLVAY SPECIALITY POLYMERS ITALY S.P.A. (IT) 2020-09-08 US disclosed
US-20200056064-A1 COATING COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2020-02-20 US disclosed
US-20190256631-A1 METHOD FOR CROSS-LINKING POLYMERS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2019-08-22 US disclosed
US-20180142050-A1 FLUOROELASTOMER COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135774-A1 FLUOROELASTOMER COMPOSITION FLNA, BET1, FLNB ACHE 3175/4885HTT 3646/4885SMN1; SMN2 1722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.