Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.56 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 13/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | GMNN | O75496 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | APEX1 | P27695 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 4/20 | 0.58 |
| ▸ | BLM | P54132 | 4/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL336306 | 1.00 | PRKCA (0.58) | PRKCAMEN1GMNNLMNAPOLB | |
| SCHEMBL337016 | 0.98 | PRKCA (0.57) | PRKCAMEN1GMNNLMNAPOLB | |
| SCHEMBL20180489 | 0.78 | ACHE (0.48) | PRKCAMEN1GMNNLMNAPOLB | |
| SCHEMBL6600083 | 0.77 | TERT (0.54) | PRKCAMEN1GMNNLMNAPOLB | |
| Iodide SCHEMBL10549487 | 0.77 | ACHE (0.44) | PRKCAMEN1GMNNLMNAPOLB | |
| SCHEMBL9976326 | 0.76 | PRKCA (0.73) | PRKCAMEN1GMNNLMNAPOLB | |
| SCHEMBL12903653 | 0.76 | PRKCA (0.84) | PRKCAMEN1GMNNLMNAPOLB | |
| SCHEMBL7256323 | 0.74 | ACHE (0.45) | PRKCAMEN1GMNNLMNAPOLB | |
| Hydrochloric Acid SCHEMBL5848626 | 0.74 | TERT (0.51) | PRKCAMEN1GMNNLMNAPOLB | |
| Iodide SCHEMBL7256178 | 0.74 | ACHE (0.41) | MEN1LMNAPOLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114747193-A | Exchange chip | 华为技术有限公司 | 2022-07-12 | — | — | CN | disclosed |