Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 6/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180275 | 0.78 | EGFR (0.50) | TDO2ABCG2ABCB1FBP1EGFR | |
| SCHEMBL20180539 | 0.77 | EGFR (0.42) | EGFRALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL20180171 | 0.76 | L3MBTL1 (0.41) | TRPV1KCNJ11MEN1KMT2A | |
| SCHEMBL20180257 | 0.75 | FBP1 (0.44) | TDO2ABCG2ABCB1FBP1EGFR | |
| SCHEMBL20180549 | 0.73 | EGFR (0.47) | TDO2ABCG2ABCB1FBP1EGFR | |
| SCHEMBL5084950 | 0.68 | KDM1A (0.50) | ALDH1A1HPGDSMN1; SMN2NPSR1KDM4E | |
| SCHEMBL8188785 | 0.68 | POLB (0.50) | ALDH1A1CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL20180219 | 0.67 | ABCG2 (0.40) | ABCG2ABCB1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL1687027 | 0.67 | RAPGEF4 (0.61) | TDO2ABCG2EGFRRAPGEF4EPAS1 | |
| SCHEMBL29961149 | 0.67 | RAPGEF4 (0.61) | TDO2ABCG2EGFRRAPGEF4EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093107-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | 주식회사 두산 | 2018-05-24 | — | — | WO | disclosed |