SCHEMBL20180645

SCHEMBL20180645

c1ccc(B2N(c3ccccc3)B(c3ccccc3)N(c3ccccc3)B(c3cccc(-c4cccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4)c3)N2c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 4/20 0.36
MEN1 O00255 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
KMT2A Q03164 3/20 0.36
ABCG2 Q9UNQ0 1/20 0.35
KDM4E B2RXH2 3/20 0.35
LMNA P02545 3/20 0.35
HTT P42858 1/20 0.35
GLA P06280 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GP6 Q9HCN6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20180755 0.77 FAAH (0.33) ALDH1A1HTTMAPK1
SCHEMBL20964251 0.76 L3MBTL1 (0.58) L3MBTL1MAPTMEN1ALDH1A1HPGD
SCHEMBL19762092 0.76 L3MBTL1 (0.58) L3MBTL1MAPTMEN1ALDH1A1HPGD
SCHEMBL19762110 0.76 L3MBTL1 (0.58) L3MBTL1MAPTMEN1ALDH1A1HPGD
SCHEMBL19762111 0.76 L3MBTL1 (0.58) L3MBTL1MAPTMEN1ALDH1A1HPGD
SCHEMBL18333555 0.76 L3MBTL1 (0.58) L3MBTL1MAPTMEN1ALDH1A1HPGD
SCHEMBL31290155 0.76 L3MBTL1 (0.58) L3MBTL1MAPTMEN1ALDH1A1HPGD
SCHEMBL19762114 0.74 L3MBTL1 (0.56) L3MBTL1MAPTMEN1ALDH1A1HPGD
SCHEMBL17720941 0.74 L3MBTL1 (0.56) L3MBTL1MAPTMEN1ALDH1A1HPGD
SCHEMBL20757456 0.74 L3MBTL1 (0.56) L3MBTL1MAPTMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180226580-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-08-09 US disclosed
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LTD (IE) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device SLC43A1, SLC6A19, AOC3 L3MBTL1 871/4885MAPT 2962/4885MEN1 3233/4885
US-20180226580-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SLCO4C1, SLCO2A1, SLCO2B1 L3MBTL1 1634/4885MAPT 1101/4885MEN1 3560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.