SCHEMBL20180647

SCHEMBL20180647

c1ccc(B2N(c3ccccc3)B(c3ccccc3)N(c3ccccc3)B(c3cccc(-c4cccc(-c5ccc6oc7ccccc7c6c5)c4)c3)N2c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.44
PLA2G4A P47712 4/20 0.44
PLA2G10 O15496 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 3/20 0.39
HPGD P15428 2/20 0.39
RAB9A P51151 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
KMT2A Q03164 1/20 0.39
PRKDC P78527 3/20 0.37
AHR P35869 2/20 0.36
LMNA P02545 1/20 0.34
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20180755 0.83 FAAH (0.33) PLA2G2APLA2G4APLA2G10ALDH1A1HSP90AA1
SCHEMBL17228732 0.80 PLA2G2A (0.58) PLA2G2APLA2G4APLA2G10SMN1; SMN2NPC1
SCHEMBL26820316 0.80 PLA2G2A (0.58) PLA2G2APLA2G4APLA2G10SMN1; SMN2NPC1
SCHEMBL15836104 0.80 PLA2G2A (0.58) PLA2G2APLA2G4APLA2G10SMN1; SMN2NPC1
SCHEMBL15836061 0.80 PLA2G2A (0.58) PLA2G2APLA2G4APLA2G10SMN1; SMN2NPC1
SCHEMBL18698077 0.80 PLA2G2A (0.58) PLA2G2APLA2G4APLA2G10SMN1; SMN2NPC1
SCHEMBL15836073 0.80 PLA2G2A (0.58) PLA2G2APLA2G4APLA2G10SMN1; SMN2NPC1
SCHEMBL17827355 0.80 PLA2G2A (0.58) PLA2G2APLA2G4APLA2G10SMN1; SMN2NPC1
SCHEMBL26820438 0.80 PLA2G2A (0.58) PLA2G2APLA2G4APLA2G10SMN1; SMN2NPC1
SCHEMBL15855167 0.80 PLA2G2A (0.57) PLA2G2APLA2G4APLA2G10SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180226580-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-08-09 US disclosed
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LTD (IE) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device SLC43A1, SLC6A19, AOC3 PLA2G2A 3181/4885PLA2G4A 3825/4885PLA2G10 3622/4885
US-20180226580-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SLCO4C1, SLCO2A1, SLCO2B1 PLA2G2A 1991/4885PLA2G4A 3381/4885PLA2G10 3547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.