Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARHGEF12 | Q9NZN5 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17603571 | 0.88 | ARHGEF12 (1.00) | ARHGEF12HTTGAASMN1; SMN2MAPT | |
| SCHEMBL15936925 | 0.88 | ARHGEF12 (1.00) | ARHGEF12HTTGAASMN1; SMN2MAPT | |
| SCHEMBL19665210 | 0.88 | ARHGEF12 (1.00) | ARHGEF12HTTGAASMN1; SMN2MAPT | |
| SCHEMBL29372342 | 0.88 | ARHGEF12 (1.00) | ARHGEF12HTTGAASMN1; SMN2MAPT | |
| SCHEMBL20175987 | 0.88 | ARHGEF12 (1.00) | ARHGEF12HTTGAASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL29557889 | 0.87 | ARHGEF12 (0.98) | ARHGEF12HTTGAASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL31717447 | 0.87 | ARHGEF12 (0.98) | ARHGEF12HTTGAASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL29557944 | 0.87 | ARHGEF12 (0.98) | ARHGEF12HTTGAASMN1; SMN2MAPT | |
| SCHEMBL24863333 | 0.78 | ARHGEF12 (0.81) | ARHGEF12HTTGAASMN1; SMN2MAPT | |
| SCHEMBL23656830 | 0.73 | ARHGEF12 (0.69) | ARHGEF12HTTGAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10405538-B2 | Platelet storage methods and compositions for same | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2019-09-10 | — | — | US | disclosed |
| US-20180139952-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME | PLATEFUSE, INC. | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180139952-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME | RHOA, ARHGDIB, ARHGDIA | ARHGEF12 9/4885HTT 2421/4885GAA 2228/4885 |
| US-10405538-B2 | Platelet storage methods and compositions for same | RHOA, ARHGDIB, ARHGDIA | ARHGEF12 9/4885HTT 2421/4885GAA 2228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.