Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARHGEF12 | Q9NZN5 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | AKT1 | P31749 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29372342 | 0.90 | ARHGEF12 (1.00) | ARHGEF12MAPTNPC1RAB9AHTT | |
| SCHEMBL15936925 | 0.90 | ARHGEF12 (1.00) | ARHGEF12MAPTNPC1RAB9AHTT | |
| SCHEMBL20175987 | 0.90 | ARHGEF12 (1.00) | ARHGEF12MAPTNPC1RAB9AHTT | |
| SCHEMBL19665210 | 0.90 | ARHGEF12 (1.00) | ARHGEF12MAPTNPC1RAB9AHTT | |
| SCHEMBL17603571 | 0.90 | ARHGEF12 (1.00) | ARHGEF12MAPTNPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL31717447 | 0.89 | ARHGEF12 (0.98) | ARHGEF12MAPTNPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL29557944 | 0.89 | ARHGEF12 (0.98) | ARHGEF12MAPTNPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL29557889 | 0.89 | ARHGEF12 (0.98) | ARHGEF12MAPTNPC1RAB9AHTT | |
| SCHEMBL24863352 | 0.79 | FAAH (0.70) | ARHGEF12MAPTNPC1RAB9AGAA | |
| SCHEMBL20180895 | 0.78 | ARHGEF12 (0.78) | ARHGEF12MAPTHTTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4116290-A1 | PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME | Platefuse, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |