Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 3/20 | 0.48 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12817357 | 0.81 | HRH4 (0.42) | ALDH1A1HPGDCXCR4KDM4EGAA | |
| SCHEMBL14820265 | 0.78 | PTPN1 (0.38) | SIGMAR1ALDH1A1HPGDCXCR4KDM4E | |
| SCHEMBL17434077 | 0.77 | NCF1 (0.62) | SIGMAR1NCF1HIF1AADRB1ADRB2 | |
| SCHEMBL15858077 | 0.77 | ADORA2A (0.47) | SIGMAR1NCF1ALDH1A1CXCR4KDM4E | |
| SCHEMBL18484400 | 0.76 | HRH4 (0.38) | SIGMAR1ALDH1A1HPGDCXCR4KDM4E | |
| SCHEMBL30575992 | 0.75 | ALDH1A1 (0.70) | NCF1ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL11817813 | 0.75 | ALDH1A1 (0.70) | NCF1ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL20181157 | 0.74 | KCNH2 (0.50) | ALDH1A1KDM4EGAAALOX15HIF1A | |
| SCHEMBL4665313 | 0.74 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1CXCR4KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL30576212 | 0.74 | ALDH1A1 (0.73) | NCF1ALDH1A1HPGDKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092725-A1 | p53 DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |