Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | SPR | P35270 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182260 | 0.85 | SPR (0.49) | ALDH1A1NPSR1TSHRLMNAHPGD | |
| SCHEMBL18229461 | 0.83 | HRH3 (0.65) | ALDH1A1LMNAGLAMAPTHRH3 | |
| SCHEMBL8812559 | 0.81 | TSHR (0.60) | TSHRANO1SPRNOTUMHTR2A | |
| SCHEMBL31127587 | 0.80 | ANO1 (0.52) | TSHRANO1MAPT | |
| SCHEMBL20182375 | 0.80 | NPSR1 (0.70) | ALDH1A1NPSR1TSHRLMNAHPGD | |
| SCHEMBL27333111 | 0.79 | HRH3 (0.67) | ALDH1A1LMNACYP2C9GLAMAPT | |
| SCHEMBL20182374 | 0.79 | NPSR1 (0.68) | ALDH1A1NPSR1TSHRLMNAHPGD | |
| SCHEMBL30275168 | 0.76 | ANO1 (0.55) | ALDH1A1TSHRLMNACYP2C9ANO1 | |
| SCHEMBL5188723 | 0.76 | TSHR (0.71) | TSHRANO1SPRNOTUMHTR1A | |
| SCHEMBL20182400 | 0.75 | SPR (0.51) | ALDH1A1NPSR1TSHRLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352326-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2019-10-17 | — | — | US | disclosed |
| WO-2018094005-A1 | MYELOPEROXIDASE IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | MPO, CAT, EPX | ALDH1A1 176/4885NPSR1 1268/4885TSHR 2257/4885 |
| US-11352326-B2 | Myeloperoxidase imaging agents | MPO, CAT, EPX | ALDH1A1 176/4885NPSR1 1268/4885TSHR 2257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.