Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689163 | 0.85 | LMNA (0.72) | GAALMNAMAPTPKMALDH1A1 | |
| SCHEMBL28289450 | 0.83 | KDM4E (0.68) | GAAGFERLMNAMAPTPKM | |
| SCHEMBL2014743 | 0.81 | KDM4E (0.56) | GAALMNAMAPTPKMALDH1A1 | |
| SCHEMBL291042 | 0.78 | KDM4E (0.71) | GAAGFERLMNAMAPTPKM | |
| SCHEMBL290852 | 0.78 | GAA (0.79) | GAAGFERLMNAMAPTPKM | |
| SCHEMBL11825251 | 0.77 | MAPT (0.47) | GAALMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL12873725 | 0.75 | GAA (0.68) | GAAGFERLMNAMAPTPKM | |
| SCHEMBL2978448 | 0.75 | MAPT (0.53) | GAALMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL290291 | 0.74 | ALDH1A1 (0.79) | GAAGFERLMNAMAPTPKM | |
| SCHEMBL291284 | 0.74 | GAA (0.55) | GAAGFERLMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106946761-A | Indole carboxamides class compound and its application | 沈阳药科大学 | 2017-07-14 | — | — | CN | disclosed |
| US-7960427-B2 | Antivirals against Hepatitis B, HIV, and influenza viruses; e.g. ethyl 2-[(benzo[d]imidazol-2-yl)thiomethyl]-6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-1H-indole-3-carboxylate | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2011-06-14 | — | — | US | disclosed |
| US-20080249155-A1 | 5-Hydroxyindole-3-Carboxylate Derivatives and Uses Thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2008-10-09 | — | — | US | disclosed |
| EP-1731506-A1 | 5-HYDROXYINDOLE-3-CARBOXYLATES DERIVATIVES AND THEIR USE | Shenyang Pharmaceutical University (CN) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249155-A1 | 5-Hydroxyindole-3-Carboxylate Derivatives and Uses Thereof | TPH1, HTR3C, IDO1 | GAA 3566/4885GFER 3330/4885LMNA 1954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.