SCHEMBL2018262

SCHEMBL2018262

O=Cc1ccc(-c2ccc(O)cc2)s1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.61
ESR1 P03372 1/20 0.61
ESR2 Q92731 1/20 0.61
CYP2E1 P05181 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2A6 P11509 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2B6 P20813 1/20 0.51
CYP2C19 P33261 1/20 0.51
PRF1 P14222 2/20 0.51
HSD17B1 P14061 5/20 0.48
HSD17B2 P37059 5/20 0.48
MAPT P10636 1/20 0.46
DPP4 P27487 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133684 0.80 APP (0.54) APPESR1ESR2CYP2E1CYP3A4
SCHEMBL9538845 0.80 APP (0.54) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL1134019 0.80 APP (0.54) APPESR1ESR2CYP2E1CYP3A4
SCHEMBL7905308 0.80 APP (0.68) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL1133750 0.80 APP (0.54) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL1133819 0.80 APP (0.54) APPESR1CYP2E1CYP3A4CYP2A6
SCHEMBL2018651 0.79 APP (0.51) APPESR1ESR2CYP2E1CYP3A4
SCHEMBL2015912 0.79 APP (0.54) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL70783 0.79 APP (0.67) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL3630228 0.78 APP (0.81) APPCYP2E1CYP3A4CYP2A6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081836-A Response near infrared fluorescent probe targeting butyrylcholinesterase and beta amyloid, and preparation method and application thereof 湖北大学 2025-06-03 CN claimed
CN-120081836-A Response near infrared fluorescent probe targeting butyrylcholinesterase and beta amyloid, and preparation method and application thereof 湖北大学 2025-06-03 CN disclosed
CN-115353495-B Preparation method and application of furazolidone metabolite AOZ-derived hapten, complete antigen and serum antibody 江西农业大学 2024-01-23 CN disclosed
CN-115353495-A Preparation method and application of furazolidone metabolite AOZ-derived hapten, complete antigen and serum antibody 江西农业大学 2022-11-18 CN disclosed
CN-112500437-B Platinum epoxide complex and preparation method and application thereof 河北医科大学 2022-08-02 CN disclosed
CN-112500437-A Platinum epoxide complex and preparation method and application thereof 河北医科大学 2021-03-16 CN disclosed
EP-2609089-A1 SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS Universität des Saarlandes (DE) 2013-07-03 EP disclosed
US-20130065897-A1 COMPOUNDS, PREPARATION AND USES THEREOF PETER MACCALLUM CANCER INSTITUTE (AU) 2013-03-14 US disclosed
EP-2515903-A1 COMPOUNDS, PREPARATIONS AND USES THEREOF Peter MacCallum Cancer Institute (AU) 2012-10-31 EP disclosed
WO-2012025638-A1 SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS Universität des Saarlandes (DE) 2012-03-01 WO disclosed
WO-2011075784-A1 COMPOUNDS, PREPARATIONS AND USES THEREOF PETER MACCALLUM CANCER INSTITUTE (AU) 2011-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065897-A1 COMPOUNDS, PREPARATION AND USES THEREOF PRF1, GZMB, SERPINB1 APP 424/4885ESR1 4805/4885ESR2 4355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.