Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.51 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | PRF1 | P14222 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30862485 | 0.90 | APP (0.70) | APPCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL32679340 | 0.90 | APP (0.47) | APPCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL29036191 | 0.90 | APP (0.70) | APPCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL3367944 | 0.87 | APP (0.76) | APPCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL13267724 | 0.83 | ESRRG (0.41) | APPCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL7010956 | 0.82 | CYP2A6 (0.54) | APPCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL1134019 | 0.80 | APP (0.54) | APPCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL7905308 | 0.80 | APP (0.68) | APPCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL1133684 | 0.80 | APP (0.54) | APPCYP2A6CYP2E1CYP3A4CYP2C9 | |
| SCHEMBL1133819 | 0.80 | APP (0.54) | APPCYP2A6CYP2E1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3226858-B1 | IMIDAZOLE-BASED ANTIMICROBIAL AGENTS | PROCOMCURE BIOTECH GMBH (AT) | 2021-02-03 | — | — | EP | disclosed |
| CN-106279132-B | 2, 4-imidazoline diketone heterocyclic derivative and preparation method and application thereof | 四川大学华西医院 | 2019-11-26 | — | — | CN | disclosed |
| US-10456379-B2 | Imidazole-based antimicrobial agents | PROCOMCURE BIOTECH GMBH (AT) | 2019-10-29 | — | — | US | disclosed |
| CN-105669660-B | Nitrogen-containing heterocycle compound and application thereof | 华东理工大学 | 2019-07-19 | — | — | CN | disclosed |
| US-10322110-B2 | Imidazole-based antimicrobial agents | PROCOMCURE BIOTECH GMBH (AT) | 2019-06-18 | — | — | US | disclosed |
| US-10314820-B2 | Imidazole-based heterocyclic compounds | PROCOMCURE BIOTECH GMBH (AT) | 2019-06-11 | — | — | US | disclosed |
| CN-107033095-B | The Oxazolidinone derivative of the structure of hydrazone containing piperazine | 沈阳红旗制药有限公司 | 2019-05-07 | — | — | CN | disclosed |
| US-20170368032-A1 | Imidazole-Based Antimicrobial Agents | PROCOMCURE BIOTECH GMBH (AT) | 2017-12-28 | — | — | US | disclosed |
| US-20170340613-A1 | Novel Imidazole-Based Heterocyclic Compounds | PROCOMCURE BIOTECH GMBH (AT) | 2017-11-30 | — | — | US | disclosed |
| US-20170334887-A1 | Imidazole-Based Antimicrobial Agents | PROCOMCURE BIOTECH GMBH (AT) | 2017-11-23 | — | — | US | disclosed |
| US-20140202537-A1 | DYE-SENSITIZED SOLAR CELL AND SENSITIZING DYE | NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) | 2014-07-24 | — | — | US | disclosed |
| US-20120283449-A1 | METHOD FOR CARRYING OUT SEQUENTIAL REACTIONS USING A HEATING MEDIUM HEATED BY MEANS OF INDUCTION | FRIESE CARSTEN (DE) | 2012-11-08 | — | — | US | disclosed |
| US-20120248428-A1 | THIENOPYRAZINE COMPOUND AND FIELD EFFECT TRANSISTOR CONTAINING THE SAME | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2012-10-04 | — | — | US | disclosed |
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |
| US-20110160192-A1 | BIARYL AMINO ACIDS AND THEIR USE IN DNA BINDING OLIGOMERS | SPIROGEN LIMITED (GB) | 2011-06-30 | — | — | US | disclosed |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2010-08-26 | — | — | US | disclosed |
| WO-2010093704-A1 | AGONISTS AND ANTAGONISTS OF THE S1P5 RECEPTOR, AND METHODS OF USES THEREOF | ABBOTT LABORATORIES (US) | 2010-08-19 | — | — | WO | disclosed |
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120248428-A1 | THIENOPYRAZINE COMPOUND AND FIELD EFFECT TRANSISTOR CONTAINING THE SAME | NR3C2, NR3C1, ADRB2 | APP 1795/4885CYP2A6 1356/4885CYP2E1 251/4885 |
| US-20170334887-A1 | Imidazole-Based Antimicrobial Agents | TLR5, NISCH, SLC11A2 | APP 3849/4885CYP2A6 3404/4885CYP2E1 2133/4885 |
| US-10456379-B2 | Imidazole-based antimicrobial agents | TLR5, NISCH, SLC11A2 | APP 3849/4885CYP2A6 3404/4885CYP2E1 2133/4885 |
| US-20110160192-A1 | BIARYL AMINO ACIDS AND THEIR USE IN DNA BINDING OLIGOMERS | PCNA, POLL, XPA | APP 647/4885CYP2A6 1800/4885CYP2E1 2379/4885 |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | S1PR5, LPAR5, S1PR1 | APP 403/4885CYP2A6 3123/4885CYP2E1 4127/4885 |
| US-10322110-B2 | Imidazole-based antimicrobial agents | ARG1, SLC11A2, IKZF3 | APP 4197/4885CYP2A6 571/4885CYP2E1 387/4885 |
| US-20170368032-A1 | Imidazole-Based Antimicrobial Agents | TLR5, NISCH, SLC11A2 | APP 3849/4885CYP2A6 3404/4885CYP2E1 2133/4885 |
| US-20120283449-A1 | METHOD FOR CARRYING OUT SEQUENTIAL REACTIONS USING A HEATING MEDIUM HEATED BY MEANS OF INDUCTION | HSF1, MYD88, HSPA2 | APP 1235/4885CYP2A6 74/4885CYP2E1 8/4885 |
| US-20170340613-A1 | Novel Imidazole-Based Heterocyclic Compounds | SLC11A2, MIF, NISCH | APP 3329/4885CYP2A6 752/4885CYP2E1 166/4885 |
| US-10314820-B2 | Imidazole-based heterocyclic compounds | MIF, SLC11A2, TLR5 | APP 3254/4885CYP2A6 506/4885CYP2E1 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.