SCHEMBL20183136

SCHEMBL20183136

C#Cc1c(C(=O)O)ccc(-c2ccccc2)c1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 2/20 0.43
PTPRC P08575 1/20 0.43
PTPN9 P43378 1/20 0.43
PTPN11 Q06124 1/20 0.43
HNF4A P41235 2/20 0.42
FOLH1 Q04609 2/20 0.41
PTPN1 P18031 3/20 0.40
FABP3 P05413 1/20 0.39
FABP4 P15090 1/20 0.39
FABP5 Q01469 1/20 0.39
CDC25B P30305 1/20 0.39
ATM Q13315 1/20 0.39
ACMSD Q8TDX5 1/20 0.39
AKR1C2 P52895 2/20 0.38
AKR1C1 Q04828 2/20 0.38
AKR1C3 P42330 1/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MMP2 P08253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4528195 0.87 FOLH1 (0.44) PTPN22PTPRCPTPN9PTPN11HNF4A
SCHEMBL27518863 0.84 PTPN22 (0.45) PTPN22PTPRCPTPN9PTPN11HNF4A
SCHEMBL5667601 0.83 FOLH1 (0.49) PTPN22PTPRCPTPN9PTPN11HNF4A
SCHEMBL1712748 0.80 PTPN22 (0.53) PTPN22CDC25BACMSDAKR1C2AKR1C3
SCHEMBL21638942 0.79 HNF4A (0.58) PTPN22PTPRCPTPN9PTPN11HNF4A
SCHEMBL5667153 0.79 ACMSD (0.46) PTPN22PTPRCPTPN9PTPN11HNF4A
SCHEMBL607218 0.78 HNF4A (0.50) HNF4AFOLH1PTPN1FABP3FABP4
SCHEMBL29921669 0.78 HNF4A (0.50) HNF4AFOLH1PTPN1FABP3FABP4
SCHEMBL21638943 0.77 PTPN22 (0.46) PTPN22PTPRCPTPN9PTPN11HNF4A
Hydrochloric Acid SCHEMBL29037897 0.77 HNF4A (0.48) HNF4AFOLH1PTPN1FABP3FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3443022-A1 SEMI-CRYSTALLINE POLYAMIDE COMPOSITION HAVING A HIGH GLASS TRANSITION TEMPERATURE AND A HIGH MELTING TEMPERATURE FOR A THERMOPLASTIC MATERIAL, PRODUCTION METHOD THEREOF AND USES OF SAME Arkema France (FR) 2019-02-20 EP disclosed
EP-3325537-A1 SEMI-CRYSTALLINE POLYAMIDE COMPOSITION HAVING A HIGH GLASS TRANSITION TEMPERATURE FOR A THERMOPLASTIC MATERIAL, PRODUCTION METHOD THEREOF AND USES OF SAME Arkema France (FR) 2018-05-30 EP disclosed
EP-3325538-A1 SEMI-CRYSTALLINE POLYAMIDE COMPOSITION HAVING A HIGH GLASS TRANSITION TEMPERATURE FOR A COMPOSITE MATERIAL, PRODUCTION METHOD THEREOF AND USES OF SAME Arkema France (FR) 2018-05-30 EP disclosed