Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.35 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CAT | P04040 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799718 | 0.84 | METAP2 (0.39) | METAP2CES2CES1MEP1BMEP1A | |
| SCHEMBL1671719 | 0.84 | CES2 (0.40) | METAP2CES2CES1MEP1BMEP1A | |
| SCHEMBL16421062 | 0.82 | CES2 (0.34) | CES2CES1ALDH1A1CA2 | |
| SCHEMBL16850296 | 0.81 | METAP2 (0.37) | METAP2MMP2MMP3MMP9PTPN1 | |
| SCHEMBL31258574 | 0.78 | CES2 (0.47) | CES2CES1FABP4TSHRCAT | |
| SCHEMBL365563 | 0.78 | CES2 (0.47) | CES2CES1FABP4TSHRCAT | |
| SCHEMBL18006678 | 0.78 | ALDH1A1 (0.42) | MEP1BMEP1ATDP1KDM4EMEN1 | |
| SCHEMBL3431160 | 0.78 | FOLH1 (0.47) | MMP2MMP3MMP9PTPN1TSHR | |
| SCHEMBL6125197 | 0.77 | METAP2 (0.46) | METAP2MMP2MMP3MMP9PTPN1 | |
| SCHEMBL2834374 | 0.75 | DPP4 (0.31) | MEP1BMEP1AFABP4CYP1A2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3149103-B1 | TRACERS | RESTRACK AS (NO) | 2018-05-30 | — | — | EP | disclosed |