Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751190 | 0.67 | HCAR2 (0.41) | — | |
| SCHEMBL34469152 | 0.67 | DPP4 (0.39) | P2RX7 | |
| SCHEMBL16038089 | 0.65 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL14044045 | 0.64 | DPP4 (0.39) | — | |
| SCHEMBL1423800 | 0.61 | CYP2C19 (0.49) | P2RX7 | |
| SCHEMBL31461381 | 0.61 | CYP11B1 (0.36) | — | |
| SCHEMBL28909974 | 0.60 | RAB9A (0.34) | — | |
| SCHEMBL14484883 | 0.59 | S1PR1 (0.37) | — | |
| SCHEMBL14970433 | 0.59 | RBP4 (0.53) | — | |
| SCHEMBL20184306 | 0.58 | P2RX7 (0.38) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970267-B3 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-30 | — | — | EP | claimed |