Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20184280 | 0.84 | PPARG (0.37) | P2RX7PIM1 | |
| SCHEMBL16093720 | 0.71 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL20184275 | 0.67 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL18860817 | 0.67 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL21239648 | 0.65 | P2RX7 (0.48) | P2RX7 | |
| SCHEMBL15019739 | 0.61 | TRPM8 (0.35) | — | |
| SCHEMBL20184283 | 0.58 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL20184289 | 0.58 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL15020409 | 0.56 | PPARG (0.39) | — | |
| SCHEMBL20184281 | 0.56 | P2RX7 (0.53) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970267-B3 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-30 | — | — | EP | claimed |