Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 1/20 | 0.53 | |
| ▸ | SSTR3 | P32745 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16599524 | 0.93 | HTR2A (0.52) | PDFSSTR3ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL1674876 | 0.81 | SSTR3 (0.64) | PDFSSTR3TGM2 | |
| SCHEMBL19209358 | 0.79 | HTR2A (0.55) | PDFSSTR3ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL20303609 | 0.79 | PDF (0.69) | PDFSSTR3ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL20303610 | 0.79 | PDF (0.69) | PDFSSTR3ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL16599526 | 0.78 | HTR2A (0.54) | PDFSSTR3ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL15676465 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1HTR2AHTT | |
| Hydrochloric Acid SCHEMBL31456028 | 0.78 | PDF (0.68) | PDFSSTR3ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL19209361 | 0.77 | HTR2A (0.55) | PDFSSTR3ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL18788631 | 0.77 | SSTR3 (0.65) | PDFSSTR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917195-B9 | SPLICEOSTATIN ANALOGS | PFIZER (US) | 2018-05-30 | — | — | EP | disclosed |