Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20185753 | 1.00 | KIF11 (0.45) | KIF11DNMT1 | |
| SCHEMBL21084963 | 0.89 | SIRT2 (0.40) | KIF11DNMT1 | |
| SCHEMBL20202835 | 0.85 | MMP13 (0.44) | KIF11DNMT1 | |
| SCHEMBL20185749 | 0.84 | KIF11 (0.39) | KIF11DNMT1 | |
| SCHEMBL20185751 | 0.84 | KIF11 (0.39) | KIF11DNMT1 | |
| SCHEMBL21084921 | 0.79 | KIF11 (0.65) | KIF11DNMT1 | |
| SCHEMBL21084920 | 0.79 | KIF11 (0.65) | KIF11DNMT1 | |
| SCHEMBL21084947 | 0.79 | KIF11 (0.65) | KIF11DNMT1 | |
| SCHEMBL20202847 | 0.77 | KIF11 (0.50) | KIF11DNMT1 | |
| SCHEMBL20202838 | 0.77 | KIF11 (0.50) | KIF11DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10413583-B2 | Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods | THE UNIVERSITY OF CHICAGO (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180147250-A1 | SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS | THE UNIVERSITY OF CHICAGO | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10413583-B2 | Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods | DNPEP, PTMS, CTH | KIF11 4826/4885DNMT1 2205/4885 |
| US-20180147250-A1 | SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS | DNPEP, PTMS, CTH | KIF11 4826/4885DNMT1 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.