Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 15/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21084940 | 0.91 | MMP13 (0.42) | MMP13KIF11SIRT2DNMT1 | |
| SCHEMBL21084941 | 0.91 | MMP13 (0.42) | MMP13KIF11SIRT2DNMT1 | |
| SCHEMBL21084966 | 0.91 | MMP13 (0.42) | MMP13KIF11SIRT2DNMT1 | |
| SCHEMBL21084958 | 0.88 | KIF11 (0.49) | KIF11DNMT1 | |
| SCHEMBL20185747 | 0.88 | KIF11 (0.49) | KIF11DNMT1 | |
| SCHEMBL8370224 | 0.88 | KIF11 (0.49) | KIF11DNMT1 | |
| SCHEMBL20202843 | 0.87 | KIF11 (0.48) | KIF11DNMT1 | |
| SCHEMBL20185753 | 0.85 | KIF11 (0.45) | KIF11DNMT1 | |
| SCHEMBL20185750 | 0.85 | KIF11 (0.45) | KIF11DNMT1 | |
| SCHEMBL8416048 | 0.83 | KIF11 (0.42) | MMP13KIF11SIRT2DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180147250-A1 | SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS | THE UNIVERSITY OF CHICAGO | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147250-A1 | SYNTHETIC SUBSTRATES FOR ENZYMES THAT CATALYZE REACTIONS OF MODIFIED CYSTEINES AND RELATED METHODS | DNPEP, PTMS, CTH | MMP13 823/4885KIF11 4826/4885SIRT2 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.