Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SDHB | P21912 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29603089 | 1.00 | NOTUM (0.50) | NOTUMKDM4EALDH1A1SDHBL3MBTL1 | |
| SCHEMBL3855311 | 0.89 | NOTUM (0.45) | NOTUMKDM4EALDH1A1SDHBL3MBTL1 | |
| SCHEMBL5520428 | 0.85 | ALDH1A1 (0.47) | NOTUMKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL6122289 | 0.84 | GPBAR1 (0.40) | NOTUMALDH1A1SDHBGPBAR1LMNA | |
| SCHEMBL6121134 | 0.83 | ATF1 (0.47) | KDM4EALDH1A1L3MBTL1GPBAR1CA12 | |
| SCHEMBL569249 | 0.82 | ALDH1A1 (0.59) | KDM4EALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL15391189 | 0.82 | NOTUM (0.51) | NOTUMKDM4EALDH1A1SDHBL3MBTL1 | |
| SCHEMBL23411999 | 0.81 | GPBAR1 (0.44) | GPBAR1HTTMAPTHIF1A | |
| SCHEMBL29723389 | 0.81 | GPBAR1 (0.44) | GPBAR1HTTMAPTHIF1A | |
| SCHEMBL28567916 | 0.81 | GPBAR1 (0.40) | NOTUMALDH1A1SDHBGPBAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709718-A1 | 6-SUBSTITUTED-3-PHENYL-ISOINDOLIN-1-ONES AS CBL-B INHIBITORS SELECTIVE OVER C-CBL | Genentech Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| US-12527325-B2 | Pesticidally active diazine-amide compounds | SYNGENTA CROP PROTECTION AG (CH) | 2026-01-20 | — | — | US | disclosed |
| EP-3947358-B1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| US-12281095-B2 | Pesticidally active diazine-amide compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-22 | — | — | US | disclosed |
| EP-3935053-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3935053-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3814332-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3814332-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| US-20220213063-A1 | N-[l-(5-BROMO-2-PYRIMIDIN-2-YL-1,2,4-TRIAZOL-3-YL)ETHYL]-2-CYCLOPROPYL-6-(TRIFLUOROMETHYL)PYRIDINE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS INSECTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-07-07 | — | — | US | disclosed |
| US-20220213063-A1 | N-[l-(5-BROMO-2-PYRIMIDIN-2-YL-1,2,4-TRIAZOL-3-YL)ETHYL]-2-CYCLOPROPYL-6-(TRIFLUOROMETHYL)PYRIDINE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS INSECTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-07-07 | — | — | US | disclosed |
| WO-2020193341-A1 | N-[1-(5-BROMO-2-PYRIMIDIN-2-YL-1,2,4-TRIAZOL-3-YL)ETHYL]-2-CYCLOPROPYL-6-(TRIFLUOROMETHYL)PYRIDINE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS INSECTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020188027-A1 | PESTICIDALLY ACTIVE AZOLE AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-09-24 | — | — | WO | disclosed |
| WO-2020182649-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-09-17 | — | — | WO | disclosed |
| WO-2020182649-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-09-17 | — | — | WO | disclosed |
| WO-2020002563-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-01-02 | — | — | WO | disclosed |
| WO-2020002563-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-01-02 | — | — | WO | disclosed |
| EP-3548495-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS CAM KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2019-10-09 | — | — | EP | disclosed |
| US-10100058-B2 | Fused heterocyclic compounds as CaM kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2018-10-16 | — | — | US | disclosed |
| WO-2018102384-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS CAM KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2018-06-07 | — | — | WO | disclosed |
| US-20180148457-A1 | FUSED HETEROCYCLIC COMPOUNDS AS CAM KINASE INHIBITORS | GILEAD SCIENCES, INC. | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10100058-B2 | Fused heterocyclic compounds as CaM kinase inhibitors | CAMK1, CAMKK1, CAMK1D | NOTUM 3747/4885KDM4E 2635/4885ALDH1A1 1512/4885 |
| US-12527325-B2 | Pesticidally active diazine-amide compounds | DDT, CHRM1, C3AR1 | NOTUM 302/4885KDM4E 2846/4885ALDH1A1 1101/4885 |
| US-20180148457-A1 | FUSED HETEROCYCLIC COMPOUNDS AS CAM KINASE INHIBITORS | CAMK1, CAMKK1, CAMK1D | NOTUM 3747/4885KDM4E 2635/4885ALDH1A1 1512/4885 |
| US-12281095-B2 | Pesticidally active diazine-amide compounds | DDT, ACHE, NIT2 | NOTUM 236/4885KDM4E 2663/4885ALDH1A1 787/4885 |
| US-20220213063-A1 | N-[l-(5-BROMO-2-PYRIMIDIN-2-YL-1,2,4-TRIAZOL-3-YL)ETHYL]-2-CYCLOPROPYL-6-(TRIFLUOROMETHYL)PYRIDINE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS INSECTICIDES | DDT, CYP2E1, CYP4B1 | NOTUM 1915/4885KDM4E 1740/4885ALDH1A1 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.