Sugi Predict

Sugi Predict / Compounds / SCHEMBL569249

SCHEMBL569249

SCHEMBL569249

COC(=O)c1cc(Cl)nc(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.59
▸ KDM4E B2RXH2 4/20 0.59
▸ CA12 O43570 3/20 0.54
▸ CA1 P00915 3/20 0.54
▸ CA2 P00918 3/20 0.54
▸ CA7 P43166 3/20 0.54
▸ CA9 Q16790 3/20 0.54
▸ CA14 Q9ULX7 3/20 0.54
▸ TDP1 Q9NUW8 3/20 0.52
▸ L3MBTL1 Q9Y468 2/20 0.52
▸ XDH P47989 2/20 0.52
▸ LMNA P02545 1/20 0.52
▸ POLB P06746 1/20 0.52
▸ GAA P10253 1/20 0.52
▸ NFKB1 P19838 1/20 0.52
▸ GFER P55789 1/20 0.52
▸ NFKB2 Q00653 1/20 0.52
▸ RELA Q04206 1/20 0.52
▸ FUT7 Q11130 1/20 0.52
▸ S1PR2 O95136 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29890892 0.98 ALDH1A1 (0.57) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL29371765 0.90 KDM4E (0.53) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL14479830 0.90 KDM4E (0.53) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL21200349 0.88 KDM4E (0.52) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL31368540 0.88 ALDH1A1 (0.52) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL1179017 0.88 ALDH1A1 (0.52) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL29867038 0.88 KDM4E (0.52) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL31287794 0.87 ALDH1A1 (0.76) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL567975 0.87 ALDH1A1 (0.76) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL4726690 0.87 ALDH1A1 (0.50) ALDH1A1KDM4ECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 569 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108148068-B Pyrazolo [1,5-a ] pyridine drug molecule with antitumor activity and preparation method and application thereof 河南科技大学第一附属医院 2020-09-15 — — CN claimed
CN-110786330-A Method for preventing and treating aphids of pepper 西南林业大学 2020-02-14 — — CN claimed
US-5851766-A Process for isolating chemically regulatable DNA sequences NOVARTIS FINANCE CORPORATION (US) 1998-12-22 — — US claimed
US-5804693-A TRANSGENIC PLANT, PLANT CELL OR PLANT TISSUE COMPRISING AN ENCODED ENZYME CAPABLE METABOLIZING SALICYLIC ACID NOVARTIS FINANCE CORPORATION (US) 1998-09-08 — — US claimed
US-5789214-A TRANSPORTATION OF PLANT TISSUES, NUCLEIC ACID PROMOTER FRAGMENTS, CODES AND EXPOSING TISSUES NOVARTIS FINANCE CORPORATION (US) 1998-08-04 — — US claimed
US-5777200-A Chemically regulatable and anti-pathogenic DNA sequences and uses thereof NOVARTIS FINANCE CORPORATION (US) 1998-07-07 — — US claimed
US-5614395-A SCREENING FOR AGROCHEMICALS HAVING THE ABILITY TO INDUCE SYSTEMIC ACQUIRED RESISTANCE IN PLANTS CIBA-GEIGY CORPORATION (US) 1997-03-25 — — US claimed
EP-0268775-B1 METHOD FOR PROTECTING PLANTS AGAINST DISEASES CIBA-GEIGY AG (CH) 1992-12-23 — — EP claimed
US-4968344-A FUNGICIDES, BACTERICIDES CIBA-GEIGY CORPORATION (US) 1990-11-06 — — US claimed
EP-0332104-A2 Chemically regulatable DNA sequences and genes and uses thereof CIBA-GEIGY AG (CH) 1989-09-13 — — EP claimed
EP-0268775-A1 Method for protecting plants against diseases CIBA-GEIGY AG (CH) 1988-06-01 — — EP claimed
CN-87106598-A Protective plant is avoided the method for disease — 1988-05-04 — — CN claimed
EP-4720061-A1 TREM2 AGONISTS F. Hoffmann-La Roche AG (CH) 2026-04-08 — — EP disclosed
US-12565494-B2 Inhibitors of human respiratory syncytial virus and metapneumovirus MERCK SHARP & DOHME LLC 2026-03-03 — — US disclosed
US-20250289793-A1 MACROCYCLIC INHIBITORS OF ATP CITRATE LYASE ESPERION THERAPEUTICS, INC. 2025-09-18 — — US disclosed
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF SCHRÖDINGER, INC. 2025-08-21 — — US disclosed
WO-1984003884-A1 N-PHENYL-N'-(PYRIDINYL-N-OXIDE)UREA PLANT REGULATORS FMC CORP (US) 1984-10-11 — — WO disclosed
US-4474602-A Substituted pyridyl compounds, herbicidal compositions and method of use THE DOW CHEMICAL COMPANY (US) 1984-10-02 — — US disclosed
EP-0081351-A1 Herbicidal triazinyl compositions with an epoxy butane and method of using THE DOW CHEMICAL COMPANY (US) 1983-06-15 — — EP disclosed
US-4137067-A Pyridine-4-carboxylic acid hydrazides for combatting phytopathogenic microorganisms and for regulating plant growth CIBA-GEIGY CORPORATION (US) 1979-01-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC ALDH1A1 4641/4885KDM4E 787/4885CA12 4848/4885
US-12565494-B2 Inhibitors of human respiratory syncytial virus and metapneumovirus NHERF1, ZC3HAV1, SARS1 ALDH1A1 4313/4885KDM4E 3725/4885CA12 1289/4885
US-20250289793-A1 MACROCYCLIC INHIBITORS OF ATP CITRATE LYASE ACLY, CS, ATP5ME ALDH1A1 792/4885KDM4E 1922/4885CA12 2026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.