SCHEMBL20187331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2675456	0.91	AR (0.44)	ESRRATTRARSCN9AMERTK
	SCHEMBL26236493	0.86	TTR (0.50)	TTRPARP10HSPB1MEN1POLB
	SCHEMBL14656419	0.85	EPAS1 (0.54)	EPAS1
	SCHEMBL14656240	0.85	EPAS1 (0.46)	TTRARSLC22A12EPAS1MEN1
	SCHEMBL19131768	0.84	TTR (0.47)	ESRRATTRARSCN9AMERTK
	SCHEMBL14661910	0.83	AR (0.50)	ESRRATTRARSLC22A12
	SCHEMBL14662035	0.83	AR (0.47)	ESRRATTRARSLC22A12EPAS1
	SCHEMBL6142767	0.83	ALDH1A1 (0.51)	TTRSCN9AHSPB1MEN1POLB
	SCHEMBL30816847	0.83	ALDH1A1 (0.51)	TTRSCN9AHSPB1MEN1POLB
	SCHEMBL875569	0.82	SLC22A12 (0.44)	SLC22A12EPAS1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.