Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187634 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL20188766 | 0.83 | MAOA (0.50) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL20187576 | 0.82 | MEN1 (0.50) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10037461 | 0.81 | MAOA (0.56) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL10037462 | 0.81 | MAOA (0.56) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL10037463 | 0.80 | MAOA (0.51) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL20190666 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL20187588 | 0.79 | L3MBTL1 (0.47) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL20189223 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL20189173 | 0.76 | MAPT (0.56) | ALDH1A1MEN1KMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |