Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ELANE | P08246 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10037461 | 0.94 | MAOA (0.56) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL20187563 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL20189238 | 0.86 | MEN1 (0.43) | ALDH1A1MAPTTDP1MAOAMAPK1 | |
| SCHEMBL20188766 | 0.85 | MAOA (0.50) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL6000950 | 0.83 | STAT3 (0.46) | ALDH1A1MAPTMAOAHPGDSMN1; SMN2 | |
| SCHEMBL10037462 | 0.79 | MAOA (0.56) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL20187666 | 0.77 | HPGD (0.51) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL10037463 | 0.76 | MAOA (0.51) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL20190666 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTTDP1TSHRMAOA | |
| SCHEMBL20189223 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTTDP1TSHRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |