Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188827 | 0.81 | PSMB11 (0.47) | HPGDLMNAALOX15ALDH1A1MAPK1 | |
| SCHEMBL20187634 | 0.77 | ALDH1A1 (0.54) | HPGDLMNACYP3A4CYP1A2ALOX15 | |
| SCHEMBL20187563 | 0.75 | ALDH1A1 (0.56) | HPGDLMNACYP3A4ALOX15HIF1A | |
| SCHEMBL20188766 | 0.73 | MAOA (0.50) | HPGDLMNACYP3A4ALOX15HIF1A | |
| SCHEMBL6000957 | 0.72 | MAPT (0.48) | HPGDLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL10037461 | 0.72 | MAOA (0.56) | HPGDLMNACYP3A4CYP1A2ALOX15 | |
| SCHEMBL10602832 | 0.71 | ALDH1A1 (0.68) | HPGDLMNACYP3A4CYP1A2ALOX15 | |
| SCHEMBL7795702 | 0.71 | MEN1 (0.62) | HPGDLMNACYP3A4ALOX15AR | |
| SCHEMBL10037463 | 0.71 | MAOA (0.51) | HPGDLMNACYP3A4ALOX15HIF1A | |
| SCHEMBL20189223 | 0.70 | ALDH1A1 (0.43) | HPGDLMNACYP3A4ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | claimed |