Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 4/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.55 |
| ▸ | AHCY | P23526 | 6/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.54 |
| ▸ | ADA | P00813 | 1/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986298 | 0.88 | AHCY (0.57) | PI4KAPI4K2BPI4K2API4KBTP53 | |
| SCHEMBL13986311 | 0.88 | AHCY (0.57) | PI4KAPI4K2BPI4K2API4KBTP53 | |
| SCHEMBL10015774 | 0.86 | AHCY (0.59) | PI4KAPI4K2BPI4K2API4KBTP53 | |
| SCHEMBL284737 | 0.86 | AHCY (0.59) | PI4KAPI4K2BPI4K2API4KBTP53 | |
| SCHEMBL5962596 | 0.86 | AHCY (0.59) | PI4KAPI4K2BPI4K2API4KBTP53 | |
| SCHEMBL23396436 | 0.86 | AHCY (0.59) | PI4KAPI4K2BPI4K2API4KBTP53 | |
| SCHEMBL5962598 | 0.86 | AHCY (0.59) | PI4KAPI4K2BPI4K2API4KBTP53 | |
| SCHEMBL896624 | 0.86 | AHCY (0.59) | PI4KAPI4K2BPI4K2API4KBTP53 | |
| SCHEMBL20794222 | 0.86 | AHCY (0.59) | PI4KAPI4K2BPI4K2API4KBTP53 | |
| SCHEMBL29362124 | 0.86 | AHCY (0.59) | PI4KAPI4K2BPI4K2API4KBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982237-B2 | Compositions and methods for reprograming non-pluripotent cells into pluripotent stem cells | HONG GUAN, LTD. (CN) | 2018-05-29 | — | — | US | disclosed |
| US-9982237-B2 | Compositions and methods for reprograming non-pluripotent cells into pluripotent stem cells | HONG GUAN, LTD. (CN) | 2018-05-29 | — | — | US | disclosed |