SCHEMBL29362124

SCHEMBL29362124

C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@@H]1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHCY P23526 7/20 0.59
▸ ADA P00813 1/20 0.55
▸ STING1 Q86WV6 1/20 0.55
▸ TP53 P04637 1/20 0.54
▸ CYP2C9 P11712 1/20 0.54
▸ NFKB1 P19838 1/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ APEX1 P27695 1/20 0.54
▸ PI4KA P42356 1/20 0.54
▸ BLM P54132 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ ADCY1 Q08828 1/20 0.54
▸ PI4K2B Q8TCG2 1/20 0.54
▸ PI4K2A Q9BTU6 1/20 0.54
▸ PI4KB Q9UBF8 1/20 0.54
▸ POLB P06746 1/20 0.54
▸ ENPP1 P22413 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5962598 1.00 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL284737 1.00 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL20794222 1.00 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL10015774 1.00 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL896624 1.00 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL23396436 1.00 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL5962596 1.00 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL13986298 0.87 AHCY (0.57) AHCYADASTING1TP53CYP2C9
SCHEMBL17833855 0.87 AHCY (0.62) AHCYADASTING1TP53CYP2C9
SCHEMBL13986311 0.87 AHCY (0.57) AHCYADASTING1TP53CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735592-A2 THERAPEUTIC METHOD FOR MODULATING COMPARTMENTED CYCLIC ADENOSINE MONOPHOSPHATE IN REACTIVE ASTROCYTES The Board of Trustees of the Leland Stanford Junior University (US) 2026-05-06 — — EP disclosed
WO-2025007065-A2 THERAPEUTIC METHOD FOR MODULATING COMPARTMENTED CYCLIC ADENOSINE MONOPHOSPHATE IN REACTIVE ASTROCYTES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-01-02 — — WO disclosed
US-12180509-B2 Methods for reprograming non-pluripotent cells into pluripotent stem cells BEIHAO STEM CELL AND REGENERATIVE MEDICINE RESEARCH INSTITUTE CO., LTD. (CN) 2024-12-31 — — US disclosed
EP-3384007-B1 IMPROVED METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS BEIHAO STEM CELL AND REGENERATIVE MEDICINE RES INSTITUTE CO LTD (CN) 2024-03-27 — — EP disclosed
CN-117157071-A Compositions comprising autophagy activators as active ingredients for preventing or treating non-syndromic autosomal dominant deafness 延世大学校产学协力团 2023-12-01 — — CN disclosed
CN-115885046-A Inducible promoters for viral vector production 阿斯克肋匹奥生物制药公司 2023-03-31 — — CN disclosed
US-11613552-B2 Pharmaceutical agents, compositions, and methods relating thereto ALLTECH, INC. (US) 2023-03-28 — — US disclosed
WO-2022054927-A1 COMPOSITION FOR AUTOPHAGY ACTIVATION 国立大学法人大阪大学 2022-03-17 — — WO disclosed
WO-2022054926-A1 AUTOPHAGY ACTIVATING COMPOSITION CONTAINING MORPHOLINE DERIVATIVE AS ACTIVE INGREDIENT 国立大学法人大阪大学 2022-03-17 — — WO disclosed
US-20220025321-A1 METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS HONG GUAN LTD. (CN) 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613552-B2 Pharmaceutical agents, compositions, and methods relating thereto PCSK9, PCSK7, PDE3A AHCY 2938/4885ADA 2058/4885STING1 4664/4885
US-20220025321-A1 METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS AHCY, BHMT, SHMT1 AHCY 1/4885ADA 59/4885STING1 1455/4885
US-12180509-B2 Methods for reprograming non-pluripotent cells into pluripotent stem cells AHCY, BHMT, SHMT1 AHCY 1/4885ADA 59/4885STING1 1455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback