Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 6/20 | 0.57 |
| ▸ | PI4KA | P42356 | 4/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.55 |
| ▸ | ADA | P00813 | 1/20 | 0.54 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986298 | 1.00 | AHCY (0.57) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20191893 | 0.88 | PI4KA (0.55) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29362124 | 0.87 | AHCY (0.59) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL284737 | 0.87 | AHCY (0.59) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5962596 | 0.87 | AHCY (0.59) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL23396436 | 0.87 | AHCY (0.59) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL896624 | 0.87 | AHCY (0.59) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5962598 | 0.87 | AHCY (0.59) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20794222 | 0.87 | AHCY (0.59) | AHCYPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10015774 | 0.87 | AHCY (0.59) | AHCYPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465544-B2 | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-12-16 | — | — | US | disclosed |
| US-20070161007-A1 | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161007-A1 | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use | DNMT1, MAT2A, MAT1A | AHCY 6/4885PI4KA 2765/4885PI4K2B 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.