SCHEMBL2019232

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14341000	1.00	THRB (0.63)	THRBTSHRPOLBAPEX1HTT
	SCHEMBL14268200	0.93	THRB (0.59)	THRBTSHRPOLBAPEX1HTT
	SCHEMBL12932676	0.89	TSHR (0.53)	THRBTSHRPOLBAPEX1HTT
	SCHEMBL11696897	0.89	TSHR (0.53)	THRBTSHRPOLBAPEX1HTT
	Succinic Acid SCHEMBL5426323	0.88	THRB (0.61)	THRBTSHRPOLBAPEX1HTT
	SCHEMBL75014	0.88	THRB (0.55)	THRBTSHRPOLBAPEX1HTT
	SCHEMBL9314009	0.88	THRB (0.79)	THRBTSHRPOLBAPEX1HTT
	SCHEMBL672102	0.88	THRB (0.79)	THRBTSHRPOLBAPEX1HTT
	SCHEMBL700642	0.88	THRB (0.79)	THRBTSHRPOLBAPEX1HTT
	SCHEMBL22166147	0.88	THRB (0.79)	THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.