Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16608658 | 0.89 | CHUK (0.36) | CHUKMAP3K14KDM1A | |
| SCHEMBL16608287 | 0.79 | DGAT1 (0.30) | — | |
| SCHEMBL20193157 | 0.78 | — | — | |
| SCHEMBL19114604 | 0.77 | PRKCG (0.37) | KDM1A | |
| SCHEMBL16608659 | 0.77 | PRKCG (0.37) | KDM1A | |
| SCHEMBL20193265 | 0.76 | GPR119 (0.39) | KDM1A | |
| SCHEMBL19626260 | 0.75 | MAP3K14 (0.39) | MAP3K14KDM1A | |
| SCHEMBL19114427 | 0.75 | CHUK (0.40) | CHUKMAP3K14 | |
| SCHEMBL19629572 | 0.74 | MAP3K14 (0.38) | MAP3K14KDM1A | |
| SCHEMBL20193232 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981963-B2 | 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-29 | — | — | US | disclosed |