Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16608487 | 0.89 | DGAT1 (0.33) | HTR6 | |
| SCHEMBL20193242 | 0.89 | CHUK (0.36) | — | |
| SCHEMBL20193251 | 0.85 | CREBBP (0.33) | — | |
| SCHEMBL19114436 | 0.85 | CHUK (0.38) | — | |
| SCHEMBL20193151 | 0.84 | CHUK (0.34) | — | |
| SCHEMBL20193179 | 0.83 | CREBBP (0.32) | — | |
| SCHEMBL20193158 | 0.83 | CHUK (0.50) | — | |
| SCHEMBL20193178 | 0.82 | L3MBTL1 (0.39) | HTR6 | |
| SCHEMBL19114543 | 0.82 | CHUK (0.35) | — | |
| SCHEMBL20193154 | 0.81 | CHUK (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981963-B2 | 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-29 | — | — | US | disclosed |