Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 12/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16608489 | 0.90 | DGAT1 (0.35) | CREBBPDYRK1BBRD4ALK | |
| SCHEMBL20193242 | 0.86 | CHUK (0.36) | — | |
| SCHEMBL20193181 | 0.86 | CHUK (0.40) | CREBBPDYRK1BALK | |
| SCHEMBL20193252 | 0.85 | HTR6 (0.33) | — | |
| SCHEMBL20193264 | 0.84 | CHUK (0.49) | — | |
| SCHEMBL20193178 | 0.82 | L3MBTL1 (0.39) | BRD4ALK | |
| SCHEMBL20193179 | 0.81 | CREBBP (0.32) | CREBBPBRD4ALKCYP2C19 | |
| SCHEMBL19114543 | 0.80 | CHUK (0.35) | CREBBP | |
| SCHEMBL20193151 | 0.78 | CHUK (0.34) | — | |
| SCHEMBL20193217 | 0.78 | DYRK1A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981963-B2 | 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-29 | — | — | US | disclosed |