SCHEMBL20194

SCHEMBL20194

CS(=O)(=O)c1cc[c]cc1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.50
PTGS2 P35354 9/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29118654 0.91 ENPP2 (0.43) ENPP2PTGS2
SCHEMBL746134 0.85 PTGS2 (0.50) ENPP2PTGS2
SCHEMBL5457984 0.80 ENPP2 (0.43) ENPP2
SCHEMBL2937729 0.80 HTT (0.47) ENPP2PTGS2
SCHEMBL2440978 0.80 MAOB (0.46) ENPP2PTGS2
SCHEMBL2440979 0.80 MAOB (0.46) ENPP2PTGS2
SCHEMBL2440976 0.80 MAOB (0.46) ENPP2PTGS2
SCHEMBL17290582 0.79 ENPP2 (0.36) ENPP2
SCHEMBL2376239 0.78 ENPP2 (0.72) ENPP2PTGS2
SCHEMBL818508 0.77 HTR6 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9410 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
CN-112574123-B JNK inhibitors, pharmaceutical compositions and uses thereof 武汉朗来科技发展有限公司 2024-06-11 CN claimed
US-20240174603-A1 MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME RAPPTA THERAPEUTICS OY (FI) 2024-05-30 US claimed
US-11987588-B2 Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2024-05-21 US claimed
CN-117980327-A Specific coupling of antibodies 杭州多禧生物科技有限公司 2024-05-03 CN claimed
US-20240116903-A1 TETRAHYDROQUINOLINE DERIVATIVE AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2024-04-11 US claimed
US-20240116910-A1 Heterocycles as WIP1 Inhibitors PMV PHARMACEUTICALS, INC. 2024-04-11 US claimed
CN-117843543-A Preparation method of alpha, alpha-difluorobutyrolactam 南京工业大学 2024-04-09 CN claimed
CN-117843519-A Preparation of difluoro ketene and method for converting difluoro ketene into difluoro acetate and difluoro acetate amide 南京工业大学 2024-04-09 CN claimed
CN-117820421-A Cyclic peptide compound and preparation method and application thereof 南开大学 2024-04-05 CN claimed
US-4147693-A βLactam antibiotics and process for their use BAYER AKTIENGESELLSCHAFT (DE) 1979-04-03 US claimed
US-4118561-A ANTIBACTERIAL, SYNERGISTIC, ANTI-CANCER ACTIVITY, ANTI-FOLIC ACID ACTIVITY AMERICAN HOME PRODUCTS CORPORATION (US) 1978-10-03 US claimed
US-4092474-A Cephalosporins having a metaloxy group in 3-substituent SHIONOGI & CO., LTD. (JA) 1978-05-30 US claimed
US-4085099-A AZO DYES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-04-18 US claimed
US-4057642-A ANTIINFLAMMATORY, RHEUMATOID ARTHRITIS MERCK & CO., INC. (US) 1977-11-08 US claimed
US-4038268-A DIAZOTIZATION, COUPLING BAYER AKTIENGESELLSCHAFT (DT) 1977-07-26 US claimed
US-4031229-A SUBSTITUTED IMIDAZOLIDINONE-PENICILLANIC ACIDS, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-06-21 US claimed
US-4026891-A HYPOTENSIVE AGENTS, ANTITHROMBOTICS, AND CARDIOTONICS BOEHRINGER INGELHEIM GMBH (DT) 1977-05-31 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3931152-A ANTITUBERCULAR AMERICAN CYANAMID COMPANY (US) 1976-01-06 US claimed