Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.41 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.41 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25667539 | 0.87 | ENPP2 (0.54) | ENPP2TGM2PIP4K2CPIP4K2AATM | |
| SCHEMBL20194 | 0.80 | ENPP2 (0.50) | ENPP2 | |
| SCHEMBL3245767 | 0.79 | MEN1 (0.58) | ATMGSK3B | |
| SCHEMBL28554532 | 0.78 | SOS1 (0.56) | CA12CA1CA2CA9 | |
| SCHEMBL2877698 | 0.78 | GSK3B (0.59) | GSK3BCA12CA1CA2CA9 | |
| SCHEMBL5458774 | 0.77 | PTGS2 (0.57) | PIP4K2ACA12CA1CA2CA9 | |
| SCHEMBL746134 | 0.77 | PTGS2 (0.50) | ENPP2 | |
| SCHEMBL24383402 | 0.76 | ENPP2 (0.43) | ENPP2TGM2PIP4K2CPIP4K2AATM | |
| SCHEMBL12467721 | 0.75 | HSD17B10 (0.44) | — | |
| SCHEMBL5923820 | 0.74 | PTGS2 (0.56) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129433-A1 | Diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129433-A1 | Diphenylamine derivatives | CCNY, CHKB, CHKA | ENPP2 4110/4885TGM2 3843/4885SMN1; SMN2 3996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.